Figure 3.
GLP-1R expression of PBMCs after LIR treatment.
Notes: (A) mRNA level analyzed by qRT-PCR; relative GLP-1R mRNA level is given as the ratio between the expression level before and after LIR treatment. Data are expressed as mean ± SEM (n=12). (B, C) Representative Western blot analysis for GLP-1R protein and the average quantification obtained by densitometric analysis of the samples before and after LIR treatment in COPD patients and non-COPD subjects. Data are expressed as mean ± SEM. **P<0.01 vs control. The statistical significance of differences observed was determined by Wilcoxon matched-pairs signed-rank test.
Abbreviations: con, control; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GLP-1R, glucagon-like peptide-1 receptor; LIR, liraglutide; PBMC, peripheral blood mononuclear cell; qRT-PCR, quantitative real-time PCR; SEM, standard error of the mean.