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. 2018 Oct 8;9:1135. doi: 10.3389/fphys.2018.01135

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Copyright © 2018 Lazarus and Harridge.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic depicting the compartmentalisation of factors that impact on aging. The assumption here is that no pathologies are present. PAE refers to Physical Activity/Exercise.