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. 2018 Jul 27;2(10):nzy065. doi: 10.1093/cdn/nzy065

TABLE 2.

Weight, energy intake, and plasma chemistry evaluations at 32 wk of dietary treatment1

P
10% Lard 10% Fish oil 41% Lard 41% Fish oil Type of fat Percentage of fat Interaction
Final weight, g 36.1 ± 1.1 [12] 34.0 ± 0.6 [12] 39.8 ± 2.0 [11] 36.5 ± 0.8 [12] 0.0314¥ 0.0138¥ 0.6136
Weight gain,2 g 14.1 ± 0.9 [12] 12.0 ± 0.5 [12] 18.1 ± 1.9 [11] 14.5 ± 0.8 [12] 0.0133¥ 0.005¥ 0.4963
Energy intake,3 kcal ⋅ body weight−1 ⋅ wk−1 70.0 ± 1.9 [8] 70.8 ± 2.1 [8] 76.1 ± 2.2 [8] 78.2 ± 3.4 [8] 0.5491 0.0109¥ 0.7866
GTT AUC, mg/dL 6928 ± 730 [12] 5555 ± 729 [12] 9277 ± 1058 [11] 5985 ± 921 [11] 0.0098¥ 0.1146 0.2721
Total cholesterol, mg/dL 107 ± 3.3 [12]†¤‡ 74.6 ± 3.3 [12]*¤ 152 ± 16.0 [11]*†‡ 70.3 ± 3.9 [12]*¤ <0.0001¥ 0.0167¥ 0.0042¥
TGs, mg/dL 48.4 ± 2.8 [12] 47.8 ± 4.6 [12] 41.8 ± 2.5 [11] 47.5 ± 6.6 [12] 0.5777 0.4524 0.4831
HDL cholesterol, mg/dL 54.8 ± 5.1 [12] 43.8 ± 3.9 [12] 72.5 ± 9.6 [11] 40.3 ± 3.3 [12] 0.0006¥ 0.2309 0.0748
LDL cholesterol, mg/dL 42.5 ± 5.4 [12]¤ 26.6 ± 3.2 [9] ¤ 77.0 ± 11.0 [10]*†‡ 23.3 ± 3.4 [10]¤ <0.0001¥ 0.0239¥ 0.0071¥
HDL cholesterol:TC 0.51 ± 0.04 [12] 0.59 ± 0.04 [12] 0.49 ± 0.51 [11] 0.58 ± 0.04 [12] 0.0692 0.7098 0.8347
HDL cholesterol:LDL cholesterol 1.6 ± 0.3 [12] 1.7 ± 0.3 [9] 1.1 ± 0.2 [10] 1.9 ± 0.3 [10] 0.0855 0.5269 0.1292
Glucose, mg/dL 135 ± 7.7 [12]¤ 138 ± 10.2 [12]¤ 208 ± 7.4 [11]*†‡ 151 ± 18.0 [12]¤ 0.0259¥ 0.0008¥ 0.0161¥
Insulin, mU/L 14.7 ± 1.8 [12] 13.0 ± 1.5 [12] 40.3 ± 10.8 [11] 16.8 ± 3.9 [12] 0.0283¥ 0.0116¥ 0.0571
HOMA-IR 4.9 ± 0.6 [12]¤ 4.3 ± 0.5 [12]¤ 21.0 ± 6.0 [11]*†‡ 6.2 ± 1.3 [12]¤ 0.0120¥ 0.0035¥ 0.0188¥
1

Values are means ± SEMs; n in brackets. Two-factor ANOVA was used to identify the difference between type, percentage, and interaction (¥P < 0.05), with Tukey-Kramer post hoc test if significant. *Different from 10% lard, P < 0.05; †different from 10% fish oil, P < 0.05; ¤different from 41% lard, P < 0.05; ‡different from 41% fish oil, P < 0.05.

2

Weight gain determined from initial diet start-day and final harvest-day weights.

3

Energy intake extrapolated from number of mice/cage.