Table 3.
Relationship between BP/BP excursions during endovascular thrombectomy to values exceeding ±20% of the reference value and 3-month modified Rankin Scale score 0-2 (final models)
| Variable | Systolic blood pressure |
Mean arterial pressure |
||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Model A: without imaging outcomes | ||||
| Default independents | ||||
| Rate of BP >120% of reference (by 1/10 min) | 1.33 (1.01–1.76) | 0.038 | 1.30 (1.01–1.66) | 0.029 |
| Rate of BP <80% of reference (by 1/10 min) | 0.85 (0.67–1.08) | 0.174 | 0.85 (0.65–1.10) | 0.218 |
| Reference BP (by 10 mm Hg) | 1.37 (1.06–1.77) | 0.013 | 1.49 (1.06–2.08) | 0.016 |
| On-admission NIHSS score (by 1 point) | 0.85 (0.78–0.93) | <0.001 | 0.86 (0.80–0.94) | <0.001 |
| TICI grade 2b-3 (vs. 0-2a) | 3.96 (1.34–11.7) | 0.009 | 3.72 (1.26–11.0) | 0.013 |
| Collaterals ≥50% as unaffected side (vs. no) | 4.62 (1.45–11.2) | 0.007 | 4.71 (1.44–15.4) | 0.006 |
| Selected independents | ||||
| Cardioembolic/unknown etiology (vs. LAA) | 0.25 (0.07–090) | 0.026 | 0.22 (0.06–0.84) | 0.018 |
| Pre-index stroke statin use | 5.88 (1.55–22.3) | 0.005 | 4.71 (1.27–17.5) | 0.013 |
| Post-index stroke statin use | 0.32 (0.12–0.82) | 0.015 | 0.34 (0.13–0.87) | 0.020 |
| Age (by 10 yr) | 0.69 (0.50–0.96) | 0.020 | 0.72 (0.52–0.99) | 0.039 |
| Model B: including ischemic lesion volume | ||||
| Default independents | ||||
| Rate of BP >120% of reference (by 1/10 min) | 1.25 (0.95–1.71) | 0.114 | 1.22 (0.95–1.61) | 0.115 |
| Rate of BP <80% of reference (by 1/10 min) | 0.88 (0.69–1.11) | 0.291 | 0.89 (0.67–1.15) | 0.371 |
| Reference BP (by 10 mm Hg) | 1.33 (1.02–1.77) | 0.034 | 1.37 (0.97–1.97) | 0.071 |
| On-admission NIHSS score (by 1 point) | 0.87 (0.79–0.95) | 0.002 | 0.88 (0.81–0.96) | 0.003 |
| TICI grade 2b-3 (vs. 0-2a) | 2.73 (0.89–9.10) | 0.079 | 2.55 (0.83–8.46) | 0.101 |
| Collaterals ≥50% as unaffected side (vs. no) | 2.95 (0.88–11.2) | 0.080 | 3.04 (0.91–11.5) | 0.071 |
| Ischemic lesion volume (by 2.718-fold) | 0.65 (0.50–0.83) | <0.001 | 0.66 (0.50–0.84) | <0.001 |
| Selected independents | ||||
| Cardioembolic/unknown etiology (vs. LAA) | 0.19 (0.05–0.69) | 0.011 | 0.16 (0.04–0.62) | 0.007 |
| Pre-index stroke statin use | 3.94 (1.08–16.8) | 0.037 | 3.48 (0.97–14.8) | 0.057 |
| Post-index stroke statin use | 0.34 (0.12–0.88) | 0.026 | 0.33 (0.12–0.87) | 0.025 |
| Age (by 10 yr) | 0.63 (0.43–0.87) | 0.005 | 0.65 (0.45–0.90) | 0.010 |
BP, blood pressure; OR, odds ratio; CI, confidence interval; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis in Cerebral Infarction; LAA, large artery atherosclerosis.