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. 2018 Sep 7;5(10):1163–1175. doi: 10.1002/acn3.629

Figure 3.

Figure 3

Receiver operating curves (ROC) of the different models discriminating specific diagnostic groups in the validation cohort. (A–C) ROC curves of the (A) FTLD vs. CON model (MFG‐E8, tTau, and Aβ 42), (B) the FTLD vs. non‐FTLD dementia models (YKL40, pTau, p/tTau, and age) and (C) the FTLD‐TDP vs. CON model (YKL40, MFG‐E8, and catalase activity) discriminating corresponding patients in the discovery (green line) and validation (blue line) cohorts. Abbreviations: FTLD, frontotemporal lobar degeneration; CON, healthy nondemented controls; TDP, TAR DNA‐binding protein 43; AD, Alzheimer's disease.