Table 4.
Effect | Odds ratio | 95% CI | P‐value |
---|---|---|---|
Race = White | |||
HSV‐1: positive vs. negative | 2.18 | 1.35–3.52 | 0.001 |
HSV‐2: positive vs. negative | 2.30 | 1.32–3.99 | 0.003 |
VCA: positive vs. negative | 10.64 | 5.77–19.62 | <0.001 |
Race = Black | |||
HSV‐1: positive vs. negative | 1.43 | 0.63–3.26 | 0.395 |
HSV‐2: positive vs. negative | 1.43 | 0.57–3.59 | 0.453 |
VCA: positive vs. negative | 6.75 | 1.43–31.91 | 0.016 |
Race = Other | |||
HSV‐1: positive vs. negative | 0.36 | 0.11–1.20 | 0.096 |
HSV‐2: positive vs. negative | 0.23 | 0.04–1.26 | 0.089 |
VCA: positive vs. negative | 1.96 | 0.52–7.37 | 0.319 |
Stratified analysis based on age | |||
Age < 15 | |||
VCA: positive vs. negative | 3.29 | 1.86–5.84 | <0.001 |
Age ≥ 15 | |||
VCA: positive vs. negative | a | ||
Stratified analysis based on DRB1 status | |||
DRB1*15:01 or 15:03 = positive | |||
HSV‐1: positive vs. negative | 0.93 | 0.47–1.84 | 0.828 |
DRB1*15:01 or 15:03 = negative | |||
HSV‐1: positive vs. negative | 1.89 | 1.17–3.03 | 0.009 |
173 of 174 cases in the older age group were positive for EBV‐VCA antibody, compared to 127 of 200 for controls. Since there was only one negative case, the model was not stable in this age group.