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. 2018 Oct 5;9:461. doi: 10.3389/fgene.2018.00461

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Copyright © 2018 O’Neill, Liao, Patel and Hammell.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detailed analysis miRNAs of interest. (A) qPCR representing fold change of miRNAs miR-184, miR-211, and miR-100 in 451Lu BRAF Resistant samples relative to 451Lu parental expression levels across replicates. (B) qPCR representing log fold change of the VIM miRNA in 451Lu BRAF Resistant vs. Parental samples and BAM gene alignment tracks across samples. (C) RNAfold predicted secondary structure of VIM intron 6 with the candidate miRNA highlighted in purple.