Figure 1. Nuclear factor kappa‐B (NF‐κB) activation.

Fold change from pre‐ to post‐hypoxia reoxygenation (H/R) in NF‐κB p65 protein in endothelial cell nuclear extracts, indicative of NF‐κB activation, with representative Western blot images shown below. H/R‐induced NF‐κB activation was prevented in cells pre‐heated at 39°C for 24 h or exposed to sera collected from human subjects who underwent 8 weeks of passive heat therapy. Data are mean ± S.E. ^* P < 0.05 vs. control conditions (37°C or 0wk).