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. 2017 May 8;42(4):436–446. doi: 10.1016/j.jgr.2017.04.013

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© 2017 The Korean Society of Ginseng, Published by Elsevier Korea LLC.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — KRGE regulates the mRNA levels of inflammatory mediators in the spinal cord of EAE rats. (A–F) Real-time polymerase chain reaction results for mRNA levels of IL-6 (A), IFN-γ (B), COX-2 (C), IGF-β1 (D), TGF-β (E), and VEGF-1 (F) the spinal cord of EAE rats. Analysis of variance test; #p < 0.01 versus sham group; *p < 0.01 versus EAE group. COX, cyclo-oxygenase; EAE, experimental autoimmune encephalomyelitis; IFN, interferon; IGF, insulin-like growth factor; IL, interleukin; KRGE, Korean Red Ginseng extract; TGF, transforming growth factor; VEGF, vascular endothelial growth factor.