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iPM detection of exosomes. (A) Snapshots of exosome adsorption onto a positive-charge-modified Au surface. (B) iPM and fluorescent images of exosomes. (C) Real-time binding curve of exosomes onto positive- or negative-charge-modified Au surface. (D) Size distribution of exosomes determined by iPM. (E) Size distribution of exosomes and exosome-liposome complex absorbed on positive-charge-modified Au surface, prepared at different exosome/liposome ratios (E/L). (Scale bar: 5 μm.)
