Figure 1.

Humoral response against cytosolic tryparedoxin peroxidase (c‐TXNPx) in chronic Chagas disease patients. Anti‐c‐TXNPx (a) and anti‐Trypanosoma cruzi (b) antibody titration was carried out in sera from patients with chronic asymptomatic (AS; n = 14) and chronic cardiac (CCC; n = 17) Chagas disease, and non‐infected individuals (NI; n = 15) by ELISA. The titre of antibodies from each individual was expressed as the sera dilution factor that corresponds to the IC ₅₀ value of the adjusted curve, which was calculated by non‐linear regression analysis. Each dot corresponds to the value from a single individual, and the horizontal line shows the median value for each group. Statistical analysis was performed using the non‐parametric Kruskal–Wallis test. Statistically significant differences are indicated (***P < 0·001).