Table 2. hpαCA and hpβCA Inhibition Data with Famotidine and Acetazolamide (AAZ) as a Standard Inhibitor, by a CO2 Hydration, Stopped-Flow Technique11.
Ki (nM)a | ||
---|---|---|
cmpd | famotidine | AAZ |
hpαCA | 20.7 | 21.4 |
hpβCA | 49.8 | 40.0 |
Mean from three different assays, by a stopped-flow technique (errors were in the range of ±5–10% of the reported values).