Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 28;293(41):15912–15932. doi: 10.1074/jbc.RA118.004861

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Rotwein.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

Figure 10. — Alignments of vertebrate IGF2 proteins. A, amino acid sequences of IGF2 from eight terrestrial vertebrates and humans in single-letter code. Differences among species are shown, with identities being depicted by dots. Dashes indicating no residue have been placed to maximize alignments. B, amino acid sequences of IGF2 from 12 fish species, lamprey, and human (70 amino acid variant) in single-letter code. Differences among species are shown, with identities being depicted by dots. Dashes (indicating no residue) have been placed to maximize alignments. C, phylogenetic tree of mature IGF2 in vertebrates. The scale bar indicates 0.1 substitutions per site, and the length of each branch approximates the evolutionary distance.