Figure 11.

Alignments of vertebrate IGF2 signal sequences. A, amino acid sequences of IGF2 signal peptides from eight terrestrial vertebrates in single-letter code. Differences are shown, and identities are indicated by dots. B, amino acid sequences of longer IGF2 signal peptides. Differences are indicated, and identities are signified by dots. A dash indicates no residue. Bold red text is identical to the short signal sequence shown in A. No longer signal peptides could be detected for turkey, zebra finch, flycatcher, or Anole lizard (= none). C, amino acid sequences of IGF2 signal peptides from 12 fish species and lamprey in single-letter code. Differences are shown, and identities are indicated by dots, and a dash signifies no residue. B and C, dashes have been placed to maximize alignments.