Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mean isotopic enrichment of metabolites in WT and LDHA/B-DKO cells. A–H, LS174T and B16 WT and LDHA/B-DKO cells were grown for 24 h with [13C6]glucose (LS174T, A and C; B16, B and D) and [13C5]glutamine (LS174T, E and G, B16, F and H). Intermediates of glycolysis and the TCA cycle (A, B, E, and F) were analyzed by GC/MS and amino acids by HPLC-MS/MS (C, D, G, and H). Three independent experiments were performed. *, p < 0.03; ***, p < 0.001; ****, p < 0.0001.
