Figure 12.

Glucose concentration contour at different times in the middle x–z plane inside and outside of the spheroid (color bar is in mM). Over the time, the possibility of necrosis increases. The simulations were carried out for $Q_{initial}=5\mathsf{\mu }\mathrm{L}/\min$, D = 500 μm and $c_{0.glucose}=11\mathrm{mM}$.