Table 3.
GO terms of the top 5% genes associated with backfat thickness
| Term | Count | p-value | Gene | Fold enrichment |
|---|---|---|---|---|
| GO:0031532~actin cytoskeleton reorganization | 5 | 8.26E-04 | MKLN1, BAIAP2, BCAS3, MYH9, DTNBP1 | 11.67 |
| GO:0040011~locomotion | 15 | 0.01 | ZNF280D, ITGA11, SCAI, DOCK8, CD151, MYH9, RUFY3, SLIT2, PTK2, NGFR, BCAS3, APBB2, ABL2, CLN6, CYP19A1 | 2.03 |
| GO:0030036~actin cytoskeleton organization | 9 | 0.01 | MKLN1, BAIAP2, PCDH15, BCAS3, MYH9, DTNBP1, ABL2, ADD2, SLIT2 | 2.90 |
| GO:0000902~cell morphogenesis | 14 | 0.01 | NOX4, MKLN1, ZNF280D, BAIAP2, DNAAF1, LRTM2, PCDH15, NGFR, RBPJ, MYH9, APBB2, DTNBP1, TRIM62, SLIT2 | 2.11 |
| GO:0000904~cell morphogenesis involved in differentiation | 10 | 0.02 | ZNF280D, LRTM2, PCDH15, NGFR, RBPJ, MYH9, APBB2, DTNBP1, TRIM62, SLIT2 | 2.55 |
| GO:1901187~regulation of ephrin receptor signaling pathway | 2 | 0.02 | ANKS1A, RBPJ | 107.38 |
| GO:0030182~neuron differentiation | 13 | 0.02 | ZNF280D, BAIAP2, LRTM2, GABRA5, PCDH15, HERC1, DTNBP1, SLIT2, TRAPPC9, NGFR, APBB2, RBPJ, ABL2 | 2.11 |
| GO:0048666~neuron development | 11 | 0.02 | ZNF280D, BAIAP2, GABRA5, LRTM2, PCDH15, NGFR, HERC1, APBB2, DTNBP1, ABL2, SLIT2 | 2.29 |
| GO:0032989~cellular component morphogenesis | 14 | 0.02 | NOX4, MKLN1, ZNF280D, BAIAP2, DNAAF1, LRTM2, PCDH15, NGFR, RBPJ, MYH9, APBB2, DTNBP1, TRIM62, SLIT2 | 1.99 |
| GO:0050804~modulation of synaptic transmission | 5 | 0.02 | GRM4, BAIAP2, RIN1, DTNBP1, RIMS4 | 4.67 |
| GO:0030030~cell projection organization | 13 | 0.02 | ZNF280D, BAIAP2, DNAAF1, LRTM2, PCDH15, NGFR, BCAS3, MYH9, HERC1, APBB2, DTNBP1, ABL2, SLIT2 | 2.03 |
| GO:0030029~actin filament-based process | 9 | 0.03 | MKLN1, BAIAP2, PCDH15, BCAS3, MYH9, DTNBP1, ABL2, ADD2, SLIT2 | 2.51 |
| GO:0010455~positive regulation of cell fate commitment | 2 | 0.03 | SPDEF, RBPJ | 71.59 |
| GO:0048699~generation of neurons | 13 | 0.04 | ZNF280D, BAIAP2, LRTM2, GABRA5, PCDH15, HERC1, DTNBP1, SLIT2, TRAPPC9, NGFR, APBB2, RBPJ, ABL2 | 1.90 |
| GO:0048667~cell morphogenesis involved in neuron differentiation | 7 | 0.04 | ZNF280D, LRTM2, PCDH15, NGFR, APBB2, DTNBP1, SLIT2 | 2.77 |
| GO:1903047~mitotic cell cycle process | 8 | 0.04 | ANKRD17, SIN3A, TUBGCP5, USP8, RAD21, CCNY, CAMK2D, CENPE | 2.48 |
| GO:0031175~neuron projection development | 9 | 0.04 | ZNF280D, BAIAP2, LRTM2, NGFR, HERC1, APBB2, DTNBP1, ABL2, SLIT2 | 2.26 |
The major gene ontology (GO) terms were neuron-related, cell morphogenesis, and actin cytoskeleton organization, and reorganization.