Table 2.
Characteristics of the study sample
| SCC | MCI | AD | |
|---|---|---|---|
| Subjects, n | 7 | 38 | 41 |
| Age, years | 69.3 (8.4) | 75.1 (8.6) | 76.4 (8.2) |
| Males | 6 (86%) | 16 (42%) | 23 (56%) |
| Educationa | 5.1 (1.5) | 5.2 (1.3) | 4.7 (1.6) |
| Median CDR score (IQR) | 0.5 (0–0.5) | 0.5 (0.5–0.5) | 1 (0.5–1.0) |
| MMSE | 28.9 (0.7) | 27.4 (1.8) | 24.4 (2.3) |
| Pentagon scoring | |||
| Correct pentagon copy | 6 (86%) | 34 (90%) | 32 (78%) |
| QSPT total (range 0–13) | 11.9 (1.5) | 11.6 (1.3) | 10.9 (2.1) |
| Gray matter volumes (in % ICV) | |||
| Frontal GMV | 10.6 (1.3) | 9.7 (1.1) | 9.4 (1.2) |
| Parietal GMV | 7.3 (1.0) | 6.6 (0.7) | 6.2 (0.7) |
| Temporal GMV | 6.7 (0.7) | 5.9 (0.8) | 5.5 (0.7) |
| Occipital GMV | 3.0 (0.4) | 2.7 (0.3) | 2.5 (0.3) |
Data are means (SD) or n (%) unless otherwise specified. SCC, subjective cognitive complaints; AD, Alzheimer's disease, GMV, gray matter volume; CDR, Clinical Dementia Rating; IQR, interquartile range; MMSE, Mini-Mental State Examination; QSPT, qualitative scoring method for the pentagon copy test; MCI, mild cognitive impairment.
a
Education scored in 7 levels according to the Dutch system, 1 = less than primary school, 7 = university degree.