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. 2018 Oct 8;11:363. doi: 10.3389/fnmol.2018.00363

Figure 2.

Figure 2

Cell type-specific contamination scores for patch-seq and dissociated cells. (A) Histogram of contamination scores of GABAergic elongated neurogliaform cells (eNGCs cells) from the Cadwell dataset (top) and analogous Ndnf cells from Tasic (middle) and Zeisel (bottom) dissociated-cell datasets. Contamination scores are specific to the expression of pyramidal cell type-specific marker genes. Dashed line at 0.5 indicates threshold used for calling single-cell contamination. (B) Same as (A), but for hippocampal GABAergic regular spiking interneurons (RS INT cells) characterized in Földy dataset (top) and Sncg cells from Tasic and Zeisel datasets. (C,D) Contamination scores, indicated by heatmap color bar on right, across multiple classes of broad cell types for Cadwell eNGC cells (C) and Földy regular spiking interneurons (D). Arrows denote same data shown in histograms in top panels of (A,B).