Table 2.
Effects of Caralluma russeliana stem extract on the levels of hematobiochemical parameters in the experimental diabetic and non-diabetic rats (n=7)
| Parameters | Treatments
|
|||
|---|---|---|---|---|
| Control | STZ | STZ + C. russeliana | C. russeliana | |
| Glucose (mg/dL) | 116.14±3.96 | 544.86±30.27a | 144.43±5.67b | 110.14±2.20b |
| Total protein (g/dL) | 6.74±0.15 | 5.86±0.33a | 6.94±0.20b | 6.59±0.12b |
| Albumin (g/dL) | 1.34±0.06 | 1.07±0.06a | 1.21±0.06 | 1.23±0.06 |
| Cholesterol (mg/dL) | 64.71±1.02 | 75.71±1.17a | 59.29±1.67ab | 42±1.22a,b |
| Triglycerides (mg/dL) | 51.43±1.94 | 101.57±6.81a | 55±4.97b | 52.29±2.97b |
| HDL-C (mg/dL) | 53±2.98 | 39.76±1.81a | 42.71±2.67a | 51.43±5.09b |
| LDL-C (mg/dL) | 7.94±0.66 | 17.51±1.92a | 7.69±1.58b | 8.69±0.91b |
| VLDL-C (mg/dL) | 23.67±0.89 | 46.71±3.12a | 25.29±2.84b | 24.07±1.36b |
| ALT (U/L) | 65.86±2.46 | 117.43±2.87a | 64±3.81b | 59.86±1.63b |
| AST (U/L) | 163.14±6.26 | 195.86±2.18a | 159.29±6.94b | 158.71±4.08b |
| ALP (U/L) | 166.14±5.63 | 473.86±15.54a | 203.43±4.12ab | 164.86±3.66b |
| Total bilirubin (mg/dL) | 0.12±0.01 | 0.19±0.01a | 0.12±0.01b | 0.11±0.01b |
| Creatinine (mg/dL) | 0.47±0.02 | 0.65±0.02a | 0.45±0.02b | 0.48±0.03b |
| BUN (mg/dL) | 52.86±2.53 | 131.29±4.35a | 51.86±5.51b | 45.43±1.63b |
| Uric acid (mg/dL) | 1.28±0.15 | 1.94±0.10a | 1.36±0.09b | 1.36±0.18b |
Notes: Values are expressed as mean±SE.
a
Significant difference from the normal control group at P<0.05.
b
Significant difference from STZ (the diabetic group) at P<0.05.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SE, standard error; STZ, streptozotocin; VLDL-C, very low-density lipoprotein cholesterol.