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miR-647 inhibited the TRAF2-mediated NF-κB signaling pathway.
Notes: A549 and H1299 cells were cotransfected with miR-647 mimics and pcDNA3/TRAF2 or the control vector. Western blot analysis of TRAF2 and p65 protein levels in whole cell lysate and nucleus (A). Luciferase reporter assays were performed to analyze NF-κB activity (B). *P<0.05.
Abbreviations: miR-647, microRNA-647; NSCLC, non-small cell lung cancer; TRAF2, TNF receptor-associated factor 2.
