Table 1.
Participant demographic and SCI history characteristics and baseline pain intensity (n=10).
| PIDN | Age | Sex | Present medications/day | Duration of SCI (month) | ASIA scale and level of SCI | Cause of SCI | Symptoms | Type of pain | Duration of pain (months) | Average pain intensity (0–10 NRS) at baseline (SD) | Average pain intensity at post-treatment | MR metabolite changes (differences between baseline and post-treatment)
|
|||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NAA/Cr | Glx/Cr | Cho/Cr | mI/Cr | ||||||||||||
| 1 | 32 | Male | – | 135 | C, C’4 | MVA | b | Below | 132 | 4.00 (0.00) | 3.00 | −0.08 | −0.03 | 0.07 | 0 |
| 2 | 21 | Male | Amitriptyline 50 mg | 48 | B, T7 | MVA | b | Below | 47 | 5.85 (0.34) | 0.00 | −0.13 | −0.06 | 0.02 | −0.04 |
| 3 | 33 | Male | Pregabalin 300 mg | 39 | A, T6 | Falling | b | Below | 12 | 5.00 (0.00) | 2.00 | −0.07 | −0.04 | 0.02 | 0.01 |
| 4 | 43 | Male | – | 105 | A, T10 | MVA | b, p | Below | 101 | 4.00 (0.00) | 3.00 | −0.04 | −0.06 | −0.01 | 0.03 |
| 5 | 41 | Male | – | 85 | A, T11 | MVA | b, p | At and below | 82 | 4.00 (0.00) | 4.00 | −0.07 | −0.01 | −0.02 | −0.03 |
| 6 | 35 | Male | Amitriptyline 100 mg and gabapentin 600 mg | 125 | B, C’4 | MVA | b | Below | 123 | 5.00 (0.00) | 4.00 | −0.08 | −0.03 | 0.07 | 0 |
| 7 | 23 | Male | – | 49 | A, T8 | Falling | b | At and below | 46 | 5.14 (0.34) | 1.00 | −0.13 | −0.06 | 0.02 | −0.04 |
| 8 | 36 | Male | – | 40 | A, T6 | MVA | b | Below | 15 | 4.00 (0.00) | 1.00 | −0.07 | −0.04 | 0.02 | 0.01 |
| 9 | 32 | Male | – | 90 | A, T11 | MVA | b, p | At and below | 92 | 5.00 (0.00) | 2.00 | −0.04 | −0.06 | −0.01 | 0.03 |
| 10 | 31 | Male | – | 89 | A, T11 | MVA | b | Below | 86 | 4.14 (0.34) | 4.00 | −0.07 | −0.01 | −0.02 | −0.03 |
| Mean | 32.70 | 80.50 | 73.60 | 4.61 | 2.40 | −0.08 | −0.04 | 0.02 | −0.01 | ||||||
| SD | 6.88 | 35.18 | 41.98 | 0.66 | 1.43 | 0.01 | 0.01 | 0.02 | 0.01 | ||||||
Abbreviations: ASIA, American Spinal Injury Association; A, complete lack of motor and sensory function below the level of injury (including the anal area); B, some sensation below the level of the injury (including anal sensation); b, burning; C, some muscle movement is spared below the level of injury, but 50 percent of the muscles below the level of injury cannot move against gravity; C’, cervical spine; Cho, choline; Cr, creatine; Glx, glutamine combined glutamate; mI, myoinositol; MVA, motor vehicle accident; NAA, N-acetylaspartate; p, paresthesia; PIDN, participant ID numbers; SCI, spinal cord injury; T, thoracic spine.