Table 2.
Brain metabolites | Time | Brain metabolites mean (SD) | Paired differences between baseline and post-treatment
|
P-value | |||
---|---|---|---|---|---|---|---|
Mean | SD | 95% confidence interval of the difference
|
|||||
Lower | Upper | ||||||
NAA/Cr | Baseline | 1.392 (0.08) | |||||
Post-treatment | 1.470 (0.09) | −0.078 | 0.031 | −0.100 | −0.056 | <0.001 | |
Glx/Cr | Baseline | 0.248 (0.03) | |||||
Post-treatment | 0.288 (0.03) | −0.040 | 0.020 | −0.054 | −0.0256 | <0.001 | |
Cho/Cr | Baseline | 0.748 (0.07) | |||||
Post-treatment | 0.732 (0.09) | 0.016 | 0.033 | −0.008 | 0.040 | 0.160 | |
mI/Cr | Baseline | 0.426 (0.02) | |||||
Post-treatment | 0.432 (0.03) | −0.006 | 0.027 | −0.025 | 0.0130 | 0.502 |
Abbreviations: Cho, choline; Cr, creatine; Glx, glutamine combined glutamate; mI, myo-inositol; NAA, N-acetylaspartate.