Figure 4. The process of mitophagy.
In response to stimuli such as nutrient deficiency, ROS and cellular aging, the mitochondrial membrane is depolarized. Damaged mitochondria are then removed through lysosomal degradation. Based on [64].
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.