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. 2018 Sep 28;9(76):34413–34428. doi: 10.18632/oncotarget.26126

Table 1. Comparison of autophagy types.

Macroautophagy Selective autophagy - mitophagy Chaperone-mediated autophagy Microautophagy
Autophagosome formation Formed Formed Not formed Not formed
Degradation of substrate in lysosome Yes Yes Yes Yes
Key proteins regulating the process BECN1, proteins from the ATG family PINK1 LAMP2 Not identified
Process selectivity Non-specific process Mitophagy - specific for mitochondria Applies only to substrates containing a KFERQ sequence Process specific to very small organelles