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. 2018 Jul 13;9(76):34213–34228. doi: 10.18632/oncotarget.25789

Figure 1. Treatment of AAV8-1.3HBV-infected mice with GM-CSF plus IFN-α combined with VACCINE (GM-CSF/IFN-α/VACCINE) decreased the infection.

Figure 1

(A) Schematic illustration of immunization workflow. Mice were immunized on day 21, 35, 49, and 70 post-infection. (B–E) At intervals up to 24 weeks, blood samples were collected at the indicated time points (week 0, 2, 4, 7, 9, 12, 16, 20, and 24) and the sera tested for HBV DNA, HBeAg and HBsAg, and HBsAb. The dotted line in E represents the assay limit of detection.