Table 3.
Correlation between MGD severity and bacteria
| Isolated bacteria | n (%)
|
P-value | |||
|---|---|---|---|---|---|
| Control (n=58) | Mild (n=8) | Moderate (n=55) | Severe (n=19) | ||
| None | 31 (53.4%) | 3 (37.5%) | 23 (41.8%) | 2 (10.5%)#,¶ | 0.012* |
| Staphylococcus (G+) | 23 (39.7%) | 5 (62.5%) | 29 (52.7%) | 12 (63.2%) | 0.218 |
| S. epidermidis | 23 (39.7%) | 5 (62.5%) | 28 (50.9%) | 11 (57.9%) | 0.358 |
| S. capitis | 2 (3.4%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.412 |
| S. aureus | 0 (0%) | 0 (0%) | 3 (5.5%) | 3 (15.8%)# | 0.026 |
| S. hominis | 0 (0%) | 0 (0%) | 3 (5.5%) | 0 (0%) | 0.192 |
| S. warneri | 0 (0%) | 0 (0%) | 0 (0%) | 1 (5.3%) | 0.093 |
| Lysinibacillus (G+) | 0 (0%) | 1 (12.5%)#,¶ | 0 (0%) | 0 (0%) | 0.001* |
| Microbacteriaceae (G+) | 6 (10.3%) | 0 (0%) | 8 (14.5%) | 3 (15.8%) | 0.611 |
| Micrococcaceae | 3 (5.2%) | 0 (0%) | 5 (9.1%) | 2 (10.5%) | 0.660 |
| Micrococcus luteus | 1 (1.7%) | 0 (0%) | 2 (3.6%) | 1 (5.3%) | 0.796 |
| Microbacterium | 2 (3.4%) | 0 (0%) | 1 (1.8%) | 1 (5.3%) | 0.821 |
| Bacillus (G+) | 1 (1.7%) | 0 (0%) | 2 (3.6%) | 1 (5.3%) | 0.796 |
| B. circulans | 0 (0%) | 0 (0%) | 1 (1.8%) | 0 (0%) | 0.669 |
| B. thermoamylovorans | 0 (0%) | 0 (0%) | 1 (1.8%) | 0 (0%) | 0.669 |
| B. cereus | 1 (1.7%) | 0 (0%) | 0 (0%) | 1 (5.3%) | 0.402 |
| Moraxella osloensis (G−) | 0 (0%) | 0 (0%) | 3 (5.5%) | 0 (0%) | 0.192 |
| Xanthomonadaceae (G−) | 0 (0%) | 0 (0%) | 1 (1.8%) | 0 (0%) | 0.669 |
| Corynebacterium (G+) | 0 (0%) | 0 (0%) | 0 (0%) | 6 (31.6%)#,¶ | <0.001* |
| C. macginleyi | 0 (0%) | 0 (0%) | 0 (0%) | 5 (26.3%)#,¶ | <0.001* |
| C. pseudodiphtheriticum | 0 (0%) | 0 (0%) | 0 (0%) | 1 (5.3%) | 0.093 |
| Paenibacillus (G+) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (5.3%) | 0.093 |
Notes: n (%): number of patients (percentage in the group of MGD severity). G+ and G− represent the Gram positive and negative bacteria, respectively.
*
P<0.05;
#
P<0.05 compared to control;
Δ
P<0.05 compared to mild;
¶
P<0.05 compared to moderate.
Abbreviation: MGD, Meibomian gland dysfunction.