Table 1.
Domains | Factors or predictors |
---|---|
Demographic and clinical context (non-modifiable) | Diagnosis, illness severity, symptoms, treatment outcomes Illness duration Age, maturity, pubertal status, or adolescent phase Injector/infuser (parent vs child, confounded with age) |
Injector or infuser (patients or parents) | Knowledge, understanding (disease, treatment) Know-how (treatment skills) Feeling capable, controllability, self-efficacy Positive beliefs: treatment necessity, expected benefits Negative beliefs: treatment concern, expected side effects, negative consequences Psychological barriers: psychological issues, negative effects, distress |
Social environment | Child–parent relationship quality Parental monitoring and supervision Parental involvement Promoting transition to self-care Social norms Social and peer support Social stigma |
Practical issues | Barriers such as issues in treatment availability, tight schedule, etc. Delivery device: burden, complexity, convenience Financial cost to the family |
Health care | Trust with health care provider Good relationship with provider Transition program Type of care: rural vs urban, country specificities |