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. 2018 Oct 9;13:6207–6221. doi: 10.2147/IJN.S176928

Figure 4.

Figure 4

AuNPs reduced α-SMA-positive CAF density in SW620 tumor.

Notes: (A) Histologic imaging illustrating the effect of AuNPs on the level of α-SMA-positive CAFs (brown) in tumor tissues. Scale bar, 100 µm. (B) Immunohistochemical analysis showed that the administration of AuNPs diminished the α-SMA-positive CAF density in SW620 tumor (n=6, **P=0.0032, Student’s t-test). Error bars indicate SEM.

Abbreviations: AuNPs, gold nanoparticles; α-SMA; alpha-smooth muscle actin; CAFs, cancer-associated fibroblasts; Ctrl, control; SEM, standard error of the mean.