Table 2.
Patients’ OS and the risk factor analysis of OS
| Characteristics | Median OS (95% CI) |
6-month OS (95% CI) |
12-month OS (95% CI) |
Log-rank P-value | aHR (95% CI)a |
Cox P-value | |
|---|---|---|---|---|---|---|---|
|
| |||||||
| Overall | 12.2 (11.1–12.7) | 94.25 (86.74–97.57) | 50.85 (38.17–62.21) | ||||
| Gender | Male | 12.3 (8.4–13.4) | 92.68 (79.00–97.58) | 53.52 (35.78–68.38) | 0.736 | ||
| Female | 12.1 (10.8–12.5) | 93.48 (81.13–97.85) | 46.90 (28.71–63.17) | ||||
| Age (years) | ≥70 | 11.1 (8.4–12.3) | 88.24 (71.63–95.41) | 31.35 (12.70–52.10) | 0.0015 | 1.79 (0.88–3.65) | 0.107 |
| <70 | 12.5 (11.3–14.1) | 96.23 (85.74–99.04) | 60.32 (44.26–73.09) | 1 | |||
| BMI (kg/m2) | <18.5 | 10.6 (7.6–12.5) | 85.29 (68.21–93.60) | 36.90 (16.96–57.10) | 0.0147 | ||
| 18.5–24 | 12.1 (12.1–13.4 | 100 (100-100) | 67.13 (48.50–80.29) | ||||
| >24 | 11.2 (6.2–16.7) | 85.71 (53.94–96.22) | 31.75 (5.56–63.41) | ||||
| Location | Head | 11.2 (9.7–12.7) | 90.38 (78.43–95.88) | 46.82 (30.22–61.80) | 0.784 | ||
| Body | 12.3 (10.8–13.4) | 89.66 (71.26–96.54) | 45.93 (24.75–64.82) | ||||
| Tail | 13.0 (12.1–17.6) | 100 (100–100) | 80.00 (20.38–96.92) | ||||
| VAS | ≥4 | 10.7 (8.7–11.6) | 90.18 (81.42–96.50) | 26.66 (13.78–41.41) | 0.0000 | 3.90 (1.76–8.62) | 0.001 |
| <4 | 14.1 (12.6–18.0) | 96.15 (75.69–99.45) | 82.42 (59.53–90.34) | 1 | |||
| KPS | ≥80 | 12.6 (11.3–14.1) | 96.55 (86.91–99.13) | 59.50 (43.02–72.76) | 0.0002 | 0.34 (0.17–0.68) | 0.02 |
| <80 | 10.6 (6.5–12.3) | 86.12 (67.31–94.59) | 33.89 (16.05–52.73) | 1 | |||
| Tumor size (cm) | ≥3 | 10.4 (7.9–11.6) | 92.68 (79.00–97.58) | 26.32 (11.35–44.08) | 0.0001 | 2.56 (1.28–5.01) | 0.007 |
| <3 | 12.9 (12.3–13.4) | 93.48 (81.13–97.85) | 68.74 (51.14–81.09) | 1 | |||
| Prior treatment | Chemotherapy | 12.1 (7.0–12.4) | 96.15 (80.52–99.27) | 49.26 (31.19–79.07) | 0.069 | ||
| Radiotherapy | 14.4 (8.4–17.6) | 100 (100–100) | 66.67 (23.08–88.36) | ||||
| Surgery | 11.3 (5.9–12.4) | 91.30 (76.49–99.47) | 53.97 (33.11–70.88) | ||||
| None | 12.3 (10.4–12.7) | 93.61 (79.17–99.46) | 51.51 (29.69–69.57) | ||||
Note:
a
Adjusted by age, VAS, KPS, and tumor size.
Abbreviations: aHR, adjusted HR; BMI, body mass index; Karnofsky performance status.