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LKAb induces human bone marrow cells to differentiate into M2 macrophages. Human total bone marrow was incubated with medium, LKAb, or M-CSF for 6 d. Cells were then stained with anti-CD11b and -CD64 as M1 type markers and anti-CD14 and -CD200R as M2 markers. Red outline: M2-type specific populations. As with mice, LKAb also induced human bone marrow to differentiate into anti-inflammatory macrophages.
