Table 2.

Hepatitic versus Cholestatic Liver Parenchymal Alterations

	A, C	A,C
	C	+/− in C
	Possible in alcoholic hepatitis	A, C
	A,C	+/− A,C
	A much greater than	C Rare
	Hepatitic: A,C	Cholestatic: +/− A,C
	+/− A; +/− C	Rare; would suggest “overlap”
	No	A much greater than
	Rarely in cirrhosis (C)	C
	No	Rare in A; + in C
Portal-based	Only C	Only C
Zone 3 perisinusoidal	Only C (NASH or ASH)	No
THV remains in central location in bridging fibrosis	Rare	Common in C

A= acute

C=chronic