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Delivery of survivin-driven or Cox-2-driven genes coding for an exogenously inducible form of caspase 9 results in cell death after post-translational product activation in survivin-expressing cells in vitro. All observed data were normalized to control transfections of CMV-driven DsRed plasmids. Open bars, HFF1 cells; shaded bars, MB49 cells; solid bars, MBT2 cells. Error bars = 1 sd. *P < 0.001 vs. corresponding no-activation group; t test (n≥4).
