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Recommendation for determining the appropriate ACMG/AMP evidence strength level for de novo occurrence(s)
| Supporting (PS2_Supporting or PM6_Supporting) |
Moderate (PS2_Moderate or PM6) |
Strong (PS2 or PM6_Strong) |
Very Strong (PS2_VeryStrong or PM6_VeryStrong) |
|---|---|---|---|
| 0.5 points | 1.0 points | 2.0 points | 4.0 points |
