Table 2. Effects of maternal fenvalerate exposure during pregnancy on anxiety-related behaviors in mouse offspring.
0 | 0.2mg/kg | 2.0mg/kg | 20.0mg/kg | F | P | |
---|---|---|---|---|---|---|
Male | ||||||
Squares across | 66.4 ± 5.8 | 75.3 ± 4.6 | 83.0 ± 5.9 | 73.6 ± 4.7 | 1.67 | 0.21 |
Total distance moved(m) | 11.7 ± 0.9 | 13.9 ± 0.8 | 14.4 ± 1.2 | 13.6 ± 0.9 | 1.55 | 0.23 |
In center duration(s) | 10.9 ± 2.6 | 11.3 ± 2.3 | 12.1 ± 1.4 | 8.7 ± 1.4 | 0.56 | 0.65 |
Number of feces | 1.3 ± 0.4 | 1.6 ± 0.5 | 2.2 ± 0.2 | 3.3 ± 0.4 | 5.67 | 0.01* |
Grooming | 1.0 ± 0.3 | 2.0 ± 0.5 | 1.4 ± 0.2 | 1.7 ± 0.5 | 1.09 | 0.38 |
Rearing/leaning | 27.8 ± 1.2 | 36.6 ± 3.3 | 39.8 ± 2.7 | 39.8 ± 4.5 | 3.32 | 0.04* |
Female | ||||||
Squares across | 68.5 ± 2.3 | 77.7 ± 7.2 | 86.9 ± 6.6 | 79.3 ± 10.2 | 2.02 | 0.14 |
Total distance moved(m) | 12.8 ± 0.5 | 12.2 ± 1.1 | 15.5 ± 1.0 | 14.8 ± 1.7 | 1.00 | 0.41 |
In center duration(s) | 10.1 ± 2.5 | 9.9 ± 1.4 | 8.5 ± 1.1 | 9.6 ± 0.8 | 0.12 | 0.95 |
Number of feces | 2.3 ± 0.7 | 2.3 ± 0.7 | 2.7 ± 0.9 | 3.8 ± 0.9 | 0.78 | 0.52 |
Grooming | 0.9 ± 0.2 | 1.0 ± 0.3 | 1.6 ± 0.2 | 1.1 ± 0.3 | 1.25 | 0.32 |
Rearing/leaning | 37.5 ± 2.1 | 36.8 ± 3.6 | 42.5 ± 3.0 | 44.8 ± 3.0 | 2.02 | 0.14 |
The Open field was carried on PND35. The data was present as mean± SEM.
* P<0.05.