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. 2018 Oct 15;13(10):e0205795. doi: 10.1371/journal.pone.0205795

Table 2. Clinical characteristics of 92 children with adenovirus pneumonia.

Symptoms & Signs Total
(n = 92)
n (%)
Non-severe group
(n = 73)
n (%)
Severe group
(n = 19)
n (%)
P value
Constitutional
Fever 87 (94.6) 69 (94.5) 18 (94.7) 0.970
Duration of fever, median (IQR)days1 5.0 (3.0–7.0) 5.0 (3.0–7.0) 5.0 (1.5–8.5) 0.662
Prolonged fever (>7 days) 21 (22.8) 16 (21.9) 5 (26.3) 0.684
Respiratory
Cough 86 (93.5) 68 (93.2) 18 (94.7) 0.803
Tachypnoea 43 (46.7) 29 (39.7) 14 (73.7) 0.008
Wheezing 8 (8.7) 4 (5.5) 4 (21.1) 0.054
Respiratory distress 62 (67.4) 47 (64.4) 15 (78.9) 0.122
Rhonchi 40 (43.5) 28 (38.4) 12 (63.2) 0.052
Crepitations 67 (72.8) 50 (68.5) 17 (89.5) 0.067
Disseminated disease
Shock 6 (6.5) 0 (0) 6 (31.6) < 0.001
ARDS2 7 (7.6) 0 (0) 7 (36.8) < 0.001
Pulmonary haemorrhage 2 (2.2) 0 (0) 2 (10.5) 0.041
Hepatitis 16 (17.4) 9 (12.4) 7 (36.8) 0.773
Extra-pulmonary
Vomiting ± diarrhoea 56 (60.9) 46 (63.0) 10 (52.6) 0.409
Conjunctivitis 10 (10.9) 8 (10.9) 2 (10.5) 0.294
Hepatomegaly 22 (23.9) 12 (16.4) 10 (52.6) 0.002
Seizures 4 (4.4) 1 (1.4) 3 (15.9) 0.027

1IQR: interquartile range

2ARDS: acute respiratory distress syndrome