Table 3. Laboratory results of 92 children with adenovirus pneumonia.
| Laboratory Data | Non-severe group (n = 73) n (%) |
Severe group (n = 19) n (%) |
P value |
|---|---|---|---|
| WBC1 (× 10cells/uL) (n = 91) | 0.160 | ||
| > 15.0 | 28 (38.9) | 4 (21.1) | |
| 5.0–11.0 | 44 (61.1) | 11 (57.9) | |
| < 5.0 | 0 (0) | 4 (21.1) | |
| Neutrophil (%), median (IQR)2 | 52 (47, 61) | 67 (59, 74) | 0.02 Z = -2.33 |
| Lymphocyte (%), median (IQR) | 34 (31, 44) | 28 (20, 35) | 0.05 Z = -1.98 |
| Monocyte (%), median (IQR) | 6.00 (5.5, 9.8) | 5.04 (4.33, 7.13) | 0.75 Z = -1.36 |
|
Haemoglobin, (g/dL) (n = 91) |
0.076 | ||
| > 11.0 | 48 (66.7) | 9 (47.4) | |
| 9.0–11.0 | 23 (31.9) | 8 (42.1) | |
| < 9.0 | 1 (1.4) | 2 (10.5) | |
| Platelet) (n = 87) < 150 × 103cells/μL | 1 (1.5) | 3 (15.8) | 0.031 |
| CRP3 (g/L) (n = 79), median (IQR) | 1.50 (1.32, 7.89) | 2.54 (1.97, 7.32) | 0.376 Z = -0.885 |
|
Albumin (g/l), median (IQR) |
29 (27, 32) | 24.58 (22, 27) | 0.007 Z = -2.33 |
| Abnormal (> 41 U/L) | |||
| ALT4 (n = 39) | 9 (39.1) | 7 (43.8) | 0.773 |
| Adenovirus type (n = 79) | |||
| 1 | 13 (21.7) | 1 (5.3) | 0.175 |
| 3 | 9 (15.0) | 1 (5.3) | 0.378 |
| 4 | 3 (5.0) | 0 (0) | 0.369 |
| 5 | 1 (1.7) | 1 (5.3) | 0.300 |
| 7 | 28 (46.7) | 15 (78.9) | 0.002 |
| Viral co-infection5 | 4 (5.5) | 0 (0) | 0.297 |
| Bacterial co-infection6 | 5 (6.8) | 1 (5.3) | 0.803 |
| Radiographic findings | |||
| Infiltrates ± consolidation | 69 (94.5) | 17 (89.5) | 0.461 |
1WBC: white blood cell
2IQR: interquartile range
3CRP: C-reactive protein
4ALT: alanine transaminase
5Viral co-infection: 3 cases of respiratory syncytial virus (RSV), 1 case of metapneumovirus
6Bacterial co-infection: 1 cases of Streptococcus pneumoniae, 3 cases of Haemophilus influenzae, 1 case of both Klebsiella pneumoniae and Acinetobacter baumanii in the non-severe group, 1 case of Haemophilus influenzae bacteraemia in the severe group.