. Author manuscript; available in PMC: 2019 Oct 1.

Published in final edited form as: Biochem Pharmacol. 2018 Aug 4;156:32–42. doi: 10.1016/j.bcp.2018.08.003

Table 3.

Absolute protein abundance and inter-individual variability of UGT2B17^a (pmol/mg microsomal protein) in human liver and intestinal microsomes (HLM and HIM).

	Mean ± SD (Range)	Fold difference^b
HLM (n=26)	1.7 ± 2.7 (0.06–9.7)	161
HIM-Average Small Intestine (n=6)	7.6 ± 6.6 (0.06–19.2)	319
HIM-Duodenum (n=6)	6.0 ± 8.2 (0.06–22.0)	366
HIM-Jejunum (n=6)	6.8 ± 6.0 (0.06–20.8)	346
HIM-Ileum (n=6)	10.8 ± 10.8 (0.06–28.7)	479
HIM-Colon (n=6)	16.2 ± 11.4 (0.06–29.5)	492

UGT2B15 abundance was 30.9±8.8 (11.8–44.7) in HLMs with 3.8-fold difference. UGT2B15 was not detected in pooled intestinal subcellular fractions and in donor-matched HIM.

fold difference from LOD (0.06 pmol/mg microsomal proteins).