Table 3. Xp genes that meet criteria for being involved in BAV/TAD.

Gene	ensembl	cdsStart—cdsEnd*	X inactivation status	Pseudogene/ Y homolog	Aorta Expression (GTEx median RPKM)	Valve Development	Rank
TIMP1	ENSG00000102265	X:47442814–47446090	Variable	No	423.6	Yes26	1
RBM3	ENSG00000102317	X:48433568–48435474	Variable	No	48.96	unknown	2
UBA1	ENSG00000130985	X:47058201–47074328	Active	No	41.44	unknown	3
INE2	ENSG00000281371	X:15805712–15805712	Active	No	12.36	unknown	4
AP1S2	ENSG00000182287	X:15845447–15870647	Mostly Active	No	8.701	unknown	5
GEMIN8	ENSG00000046647	X:14027031–14039597	Mostly Active	No	6.69	unknown	6
CA5B	ENSG00000169239	X:15768146–15800787	Variable	No	5.198	unknown	7
NHS	ENSG00000188158	X:17653686–17750584	Mostly Active	No	4.852	unknown	8
TRAPPC2	ENSG00000196459	X:13732525–13738082	Mostly Active	No	4.289	unknown	9
CA5BP1	ENSG00000186312	X:15721474–15721474	Active	No	3.813	unknown	10
CTPS2	ENSG00000047230	X:16608915–16721025	Mostly Active	No	3.593	unknown	11
INE1	ENSG00000224975	X:47065254–47065254	Active	No	2.09	unknown	12
TCEANC	ENSG00000176896	X:13680627–13681683	Mostly Active	No	0.4852	unknown	13
PPEF1	ENSG00000086717	X:18725899–18845605	Variable	No	0.05353	unknown	14
GRPR	ENSG00000126010	X:16142076–16170768	Mostly Active	No	0.02957	unknown	15
FAM9C	ENSG00000187268	X:13056559–13061908	Active	No	0.005627	unknown	16

*Position on the X chromosome; cdsStart, start of coding sequence; cdsEnd, end of coding sequence, hg19