Table 7. Karyotypes of the TS cohort.

Karyotype	N	TIMP1 copy number
45,X	109	1.0
45,X/46,XY	15	1.0
46,X,i(Xq)	13	1.0
45,X/46,X,i(Xq)	7	1.0
45,X[50%]/47,XXX[50%]*	4	2.0
45,X [50%]/46,X,ring(X)[50%]	2	1.5
46,X,ring(X), small	2	1.0
45X/46,X,i(Xq)/47,XXX*	1	2.0
46,X,ring(Xp11.1q28)[11%]/46,XX[89%]*	1	1.9
45,X[30%]/46,XX[70%]	1	1.7
45,X[30%]/46,XX[70%]	1	1.7
45,X[32%]/46,XX[68%]	1	1.7
45,X[35%]/46,XX[65%]	1	1.7
45,X[41%]/46,XX[59%]	1	1.6
45,X/46,X,del(Xq21.1)*	1	1.5
45,X[55%]/46,XX[45%]	1	1.5
45,X[65%]/46,XX[35%]	1	1.4
45,X[63%]/46,X,del(Xq11.23)[37%]	1	1.4
45,X[64%]/46,X,del(Xq22q24)[36%]	1	1.4
45,X[72%]/46,XX[28%]	1	1.3
45,X[75%]/46,XX[25%]	1	1.3
45,X[74%]/46,del(Xq13.1)[26%]	1	1.3
45,X[75%]/46,X,ring(X)[25%]	1	1.3
45, X[80%]/46,X,ring(X)[20%]	1	1.2
45,X[82%]/46,XX[18%]	1	1.2
45,X[84%]/46,XX[16%]	1	1.2
45,X[85%]/46,XX[15%]	1	1.2
45,X[85%]/46,XX[16%]	1	1.2
45,X[81%]/46,X,psuidic(Xq21)[19%]*	1	1.2
45,X[82%]/46,del(Xq22)[18%]*	1	1.2
45,X[82%]/46,X,del(Xp22.3p11.4)[18%]	1	1.2
45,X[83%]/46,X,ring(X)[17%]	1	1.2
45,X[85%]/46X,ring(X)[15%]	1	1.2
45,X[88%]/46,XX[12%]	1	1.1
45,X[88%]/46,X,del(Xq13.1)[12%]	1	1.1
45,X,add(15)(p11.2)*	1	1.0
45,X/46,X,+mar*	1	1.0
45,X[20%]/46,X,i(Xq)[80%]*	1	1.0
45,X[82%]/46,X,del(Xp)[18%]	1	1.0
45,X [86%]/ 46,X +mar [13%]*	1	1.0

*Clinical karyotype

N; number of subjects