Table 2.
Normal (n=76) | Osteopenia (n=89) | Normal vs. Osteopenia P-value | Osteoporosis (n=46) | Normal vs. Osteoporosis P-value | |
---|---|---|---|---|---|
Age (mean) | 55 ± 12 | 59 ± 13 | 0.06 | 67 ± 9 | 0.0001 |
Female sex | 17/76 (22%) | 26/89 (29.2%) | 0.37 | 26/46 (56.6%) | 0.0001 |
Menopause | 10 / 14 (71.4%) | 22/26 (84.6%) | 0.41 | 25/25 (100%) | 0.012 |
Body mass index (mean) | 25 ± 4 | 24 ± 3 | 0.05 | 22 ± 3 | 0.001 |
Pathological fractures | 2/68 (2.9%) | 8/86 (9.3%) | 0.18 | 3/42 (7.1%) | 0.36 |
Length of disease (mean) | 81 ± 97 | 76 ± 79 | 0.76 | 98 ± 99 | 0.38 |
Advanced-marked disease | 14/67 (20.8%) | 17/85 (20%) | 1 | 4 /41(9.7%) | 0.18 |
Diabetes | 35/76 (46%) | 27/87 (31%) | 0.05 | 15/45 (33.3%) | 0.18 |
FE < 200 mcg/g > 100 mcg/g | 37/63 (58.7%) | 44/76 (57.9%) | 1 | 20/40 (50%) | 0.42 |
FE < 100 mcg/g | 25/63 (39.6%) | 34/76 (44.7%) | 0.6 | 13/40 (32.5%) | 0.53 |
PERT | 37/76 (48.6%) | 54/89 (60.6%) | 0.15 | 25/45 (55%) | 0.57 |
Active smoking | 40/76 (52%) | 42/87 (48.2%) | 0.63 | 22/44 (50%) | 0.85 |
Pack years > 20 | 30/45 (66%) | 32/46 (69.5%) | 0.82 | 18/23 (78%) | 0.40 |
Alcoholic aetiology | 36/76 (47.3%) | 37/87 (42.5%) | 0.63 | 18/45 (40%) | 0.45 |
Vitamin D deficiency ( < 20 ng/ml) | 43/74 (58.1%) | 50/87 (57.5%) | 1 | 22/43 (51.2%) | 0.56 |
Vitamin D levels ng/ml (mean) | 19 ± 12 | 19 ± 12 | 0.86 | 23.1 ± 14 | 0.13 |
Vitamin K deficiency ( < 0.2 ng/ml) | 20/65 (30.7%) | 23/77 (29.8%) | 1 | 13/36 (36.1%) | 0.66 |
Vitamin K levels ng/ml (mean) | 0.57 ± 0.58 | 0.79 ± 1.18 | 0.17 | 0.44 ± 0.47 | 0.26 |
Mg levels mg/dl (mean) | 1.82 ± 0.39 | 1.77 ± 0.44 | 0.49 | 1.84 ± 0.48 | 0.78 |
Mg deficiency | 9/66 (13.6%) | 14/76 (18.4%) | 0.49 | 6/38 (15.7%) | 0.77 |
Ca levels mg/dl (mean) | 8.78 ± 1.77 | 9.2 ± 1.96 | 0.92 | 9.28 ± 1.35 | 0.52 |
Calcium deficiency | 9/69 (13%) | 10/83 (12%) | 1 | 5/43 (11.6%) | 1 |
PTH levels pg/ml (mean) | 43 ± 16 | 50 ± 23 | 0.06 | 70 ± 62 | 0.002 |
PTH above normal | 4/60 (6.6%) | 15/79 (18.9%) | 0.04 | 13/36 (36%) | 0.001 |
CRP levels mg/dl (mean) | 6.4 ± 16 | 3 ± 6 | 0.15 | 2.46 ± 4 | 0.29 |
CRP above normal | 28/44 (63.6%) | 32/52 (61.5%) | 1 | 10/19 (52.6%) | 0.57 |
Data are presented as rate or as mean ( ± SD)