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. 2018 Oct 15;9(10):197. doi: 10.1038/s41424-018-0066-8

Table 2.

Differences among CP patients with normal bone mineral density, osteopenia or osteoporosis

Normal (n=76) Osteopenia (n=89) Normal vs. Osteopenia P-value Osteoporosis (n=46) Normal vs. Osteoporosis P-value
Age (mean) 55 ± 12 59 ± 13 0.06 67 ± 9 0.0001
Female sex 17/76 (22%) 26/89 (29.2%) 0.37 26/46 (56.6%) 0.0001
Menopause 10 / 14 (71.4%) 22/26 (84.6%) 0.41 25/25 (100%) 0.012
Body mass index (mean) 25 ± 4 24 ± 3 0.05 22 ± 3 0.001
Pathological fractures 2/68 (2.9%) 8/86 (9.3%) 0.18 3/42 (7.1%) 0.36
Length of disease (mean) 81 ± 97 76 ± 79 0.76 98 ± 99 0.38
Advanced-marked disease 14/67 (20.8%) 17/85 (20%) 1 4 /41(9.7%) 0.18
Diabetes 35/76 (46%) 27/87 (31%) 0.05 15/45 (33.3%) 0.18
FE < 200 mcg/g > 100 mcg/g 37/63 (58.7%) 44/76 (57.9%) 1 20/40 (50%) 0.42
FE < 100 mcg/g 25/63 (39.6%) 34/76 (44.7%) 0.6 13/40 (32.5%) 0.53
PERT 37/76 (48.6%) 54/89 (60.6%) 0.15 25/45 (55%) 0.57
Active smoking 40/76 (52%) 42/87 (48.2%) 0.63 22/44 (50%) 0.85
Pack years > 20 30/45 (66%) 32/46 (69.5%) 0.82 18/23 (78%) 0.40
Alcoholic aetiology 36/76 (47.3%) 37/87 (42.5%) 0.63 18/45 (40%) 0.45
Vitamin D deficiency ( < 20 ng/ml) 43/74 (58.1%) 50/87 (57.5%) 1 22/43 (51.2%) 0.56
Vitamin D levels ng/ml (mean) 19 ± 12 19 ± 12 0.86 23.1 ± 14 0.13
Vitamin K deficiency ( < 0.2 ng/ml) 20/65 (30.7%) 23/77 (29.8%) 1 13/36 (36.1%) 0.66
Vitamin K levels ng/ml (mean) 0.57 ± 0.58 0.79 ± 1.18 0.17 0.44 ± 0.47 0.26
Mg levels mg/dl (mean) 1.82 ± 0.39 1.77 ± 0.44 0.49 1.84 ± 0.48 0.78
Mg deficiency 9/66 (13.6%) 14/76 (18.4%) 0.49 6/38 (15.7%) 0.77
Ca levels mg/dl (mean) 8.78 ± 1.77 9.2 ± 1.96 0.92 9.28 ± 1.35 0.52
Calcium deficiency 9/69 (13%) 10/83 (12%) 1 5/43 (11.6%) 1
PTH levels pg/ml (mean) 43 ± 16 50 ± 23 0.06 70 ± 62 0.002
PTH above normal 4/60 (6.6%) 15/79 (18.9%) 0.04 13/36 (36%) 0.001
CRP levels mg/dl (mean) 6.4 ± 16 3 ± 6 0.15 2.46 ± 4 0.29
CRP above normal 28/44 (63.6%) 32/52 (61.5%) 1 10/19 (52.6%) 0.57

Data are presented as rate or as mean ( ± SD)