Fig. 6. Regressing tumors display significant alterations in gene expression and enrichment of type I interferon response, p53, and TNF/death receptor signaling networks.

Total RNA from three Cre and three IKOβ tumors from different mice were subjected to RNA sequencing. a Heatmap showing total gene expression. b Gene set enrichment analysis with top 40 statistically significant (FDR < 0.1), positively enriched pathways displayed