Table 1.

Ability of subtypes to distinguish between different genotypes in symptomatic mutation carriers in GENFI using the SuStaIn subtypes in Fig. 2a

	GRN	MAPT	C9orf72
Asymmetric frontal (threshold p > 0.65)	93% (13)	9% (1)	4% (1)
Temporal (threshold p > 0.35)	0% (0)	91% (10)	21% (5)
Frontotemporal	0% (0)	0% (0)	42% (10)
Subcortical	7% (1)	0% (0)	33% (8)
Accuracy	93% (13/14)	91% (10/11)	75% (18/24)

Each entry is the percentage (number) of participants of a particular genotype assigned to that subtype. The final row indicates the percentage (fraction) of participants assigned to the correct subtype from each genotype. The results show that SuStaIn can accurately discriminate genotypes, validating the ability of SuStaIn to identify distinct phenotypes that align with known genetic groups