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. 2018 Oct 9;9:1007. doi: 10.3389/fphar.2018.01007

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Copyright © 2018 Zhang, Zhang, Fu, Zhang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IL-6 concentrations over time. IL-6, interleukin-6; Group C, the control group; Group U, the ulinastatin group. ^∗P < 0.05 from T0 in group C and group U (statistically significant), #P < 0.05 from group U (statistically significant). T0, = before skin incision, T1 = the end of operation, and T2 and T3 = 24 and 72 h postoperative.