FIGURE 7.

E2 promotes axon remyelination in regeneration sciatic nerve. (A) Representative transmission electron micrographs, obtained at 2 and 3 weeks post-surgery, of regenerated nerve in the OVX, OVX treated with E2, sham, sham treated with E2 groups, scale bar, 0.6 μm. (B) Histograms comparing the number of myelin sheath layers and the thickness of the myelin sheath among the OVX, OVX treated with E2, sham, sham treated with E2 groups. ^∗∗p < 0.01 versus vehicle. Two-way ANOVA, n = 5 rats per group. All the data are mean ± SEM.