Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 9;9:2198. doi: 10.3389/fimmu.2018.02198

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Jog, Chakravarty, Guthridge and James.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

vIL-10 does not redirect macrophage polarization. Monocytes from healthy donors were differentiated into macrophages with M-CSF for 6 days. Macrophages were treated with IFNγ (M1 polarization), IL4 (M2a polarization), hIL-10 (M2c polarization), or vIL-10 for 24 h. Surface expression of (A) HLA-DR, (B) CD86, (C) CD163, and (D) CD16 was measured by flow cytometry. Data are presented as fold change over basal, such that values >1 indicate an increase and values < 1 indicate a decrease in expression. n = 3, ^*p < 0.05, ^**p < 0.01.