Table 1.
Comparison of signalment, complete blood count, biochemistry and venous blood gas variables between control and clinical dogs
| Variable | Reference range | Control (n = 35) | Clinical (n = 22) | P value |
|---|---|---|---|---|
| Gender | MI: 4 [11%] MC: 8 [23%] FI: 15 [43%] FS: 8 [23%] |
MI: 4 [18%] MC: 8 [36%] FI: 0 [0%] FS: 10 [46%] |
.001 | |
| 25(OH)D (nmol/L) | 60‐215 | 132 [81‐209] (n = 35) | 79 [33‐125] (n = 22) | <.001 |
| PTH (pmol/L) | 0.5‐5.8 | 1.5 [0.8‐6.7] (n = 19) | 0.5 [0.3‐1.5](n = 21) | <.001 |
| iCa (mmol/L) | 1.25‐1.45 | 1.16 [1.05‐1.29] (n = 19) | 1.30 [1.08‐1.45] (n = 21) | <.001 |
| pH | 7.39‐7.49 | 7.35 [7.32‐7.44] (n = 9) | 7.43 [7.25‐7.56] (n = 16) | .006 |
| pCO2 | 23.1‐37.1 | 39.1 [30.7‐41.7] (n = 8) | 27.2 [21.2‐34.8] (n = 18) | <.001 |
| HCO3 | 16‐24 | 21.7 [20.3‐23.2] (n = 8) | 19.0 [13.6‐21.8] (n = 18) | <.001 |
| Lactate | 0.44‐2.93 | 0.9 [0.8‐2.3] (n = 8) | 1.9 [0.6‐9.3] (n = 17) | .006 |
| WBC (×103/μL) | 6.0‐17.0 | 6.2 [3.7‐16.2] (n = 25) | 17.0 [8.4‐41.8] (n = 13) | <.001 |
| Neutrophils (×103/μL) | 3.0‐11.5 | 3.9 [1.8‐12.8] (n = 25) | 13.9 [5.4‐35.1] (n = 13) | <.001 |
| Monocytes (×103/μL) | 0.2‐1.4 | 0.2 [0.04‐1.0] (n = 25) | 0.9 [0.2‐1.9] (n = 13) | <.001 |
| PLT (×103/μL) | 200‐900 | 231 [174‐400] (n = 25) | 333 [160‐425] (n = 13) | .008 |
| Creat (mg/dL) | 0.5‐1.5 | 0.9 [0.6‐1.5] (n = 16) | 0.7 [0.5‐1.1] (n = 21) | .002 |
| TP (g/dL) | 5.1‐7.0 | 6.0 [5.5‐6.4] (n = 9) | 6.9 [5.4‐7.5] (n = 12) | .004 |
| Potassium (mmol/L) | 3.9‐5.5 | 3.9 [3.5‐4.4] (n = 16) | 4.3 [3.6‐4.9] (n = 21) | .02 |
| AlkP (U/L) | 7‐92 | 33 [22‐143] (n = 9) | 80 [41‐850] (n = 14) | .04 |
Results are presented as median (range) for all continuous variables, and as number of dogs (percentage) for categorical variables. Only values which had a significant P value were included (significance level set at P < .05). MI, male intact; MC, male castrated; FI, female intact; FS, female spayed; 25(OH)D, 25‐hydroxyvitamin D; PTH, parathyroid hormone; Ica, ionized calcium; pCO2, partial pressure carbon dioxide; HCO3, bicarbonate; WBC, white blood cell; PLT, platelet; creat, creatinine; TP, total protein; AlkP, alkaline phosphatase.