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. 2018 Oct 9;9:2374. doi: 10.3389/fmicb.2018.02374

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Copyright © 2018 Bouillaguet, Manoil, Girard, Louis, Gaïa, Leo, Schrenzel and Lazarevic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OTUs differentially represented between PAP and SAP root samples. OTUs with significant changes (Wilcoxon rank-sum test, P < 0.05) and a minimum average relative abundance ≥0.5%) are presented. Boxplots show the first and third quartile (top and bottom edges of the rectangle) divided by median. Whiskers correspond to the highest and lowest values within 1.5× the interquartile range. Outliers are shown as circles. ^∗0.01 < P < 0.05; ^∗∗0.001 < P < 0.01; ^∗∗∗P < 0.001. PAP, primary apical periodontitis; SAP, secondary apical periodontitis.