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. 2018 Oct 9;9:2089. doi: 10.3389/fimmu.2018.02089

Figure 2.

Figure 2

Knockout Eogt aggravates concanavalin-A induced liver injury. (A) Schematic outline of concanavalin-A (Con A) administration in Eogt+/+ and Eogt−/− rats. (B) ALT and AST levels in Eogt+/+ and Eogt−/− rats after Con-A injection at 0, 12, 24, 48, and 72 h; (C) Western blot analysis of cleaved caspases 3 and 7 in the liver of Eogt+/+ and Eogt−/− rats after Con-A injection at 0, 12, 24, and 48 h; (D) Western blot analysis of NALP2 protein levels in the liver of Eogt+/+ and Eogt−/− rats after Con-A injection at 0 and 12 h; (E) Quantification of NALP2 protein expression in (D). (F) Representative H and E staining of liver sections after Con-A injection at 0, 12, 24, and 48 h. *p < 0.05; **p < 0.01, vs. WT control group.