Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential mechanisms leading to neurodegeneration. The picture summarizes the major heme-regulated processes that might be relevant during neurodegeneration. The alteration of intracellular labile heme may affect cell proteostasis, oxidative phosphorylation, ion channels function and/or induce oxidative stress, leading to neurodegeneration.
